Annotation Detail
Information
- Associated Genes
- WRN
- Associated Variants
-
SOAT2 p.Glu14Gly (p.E14G)
(
ENST00000301466.8 )
NC_000019.10:g.44905579T>G
APOB p.Ala618Val (p.A618V) ( ENST00000233242.5, ENST00000399256.4 )
rs10865710 ( ENST00000309576.11, ENST00000397010.7, ENST00000397015.7, ENST00000397026.7, ENST00000643197.2, ENST00000643888.2, ENST00000644622.2, ENST00000651735.1, ENST00000652098.1, ENST00000652431.1, ENST00000681982.1, ENST00000682446.1, ENST00000683586.1 )
TNF c.-1037C>T
WRN p.Cys1367Arg (p.C1367R) ( ENST00000298139.7 )
rs883484
SOAT2 p.Glu14Gly (p.E14G) ( ENST00000301466.8 )
NC_000019.10:g.44905579T>G
APOB p.Ala618Val (p.A618V) ( ENST00000233242.5, ENST00000399256.4 )
rs10865710 ( ENST00000309576.11, ENST00000397010.7, ENST00000397015.7, ENST00000397026.7, ENST00000643197.2, ENST00000643888.2, ENST00000644622.2, ENST00000651735.1, ENST00000652098.1, ENST00000652431.1, ENST00000681982.1, ENST00000682446.1, ENST00000683586.1 )
TNF c.-1037C>T
WRN p.Cys1367Arg (p.C1367R) ( ENST00000298139.7 )
rs883484 - Associated Disease
- Chronic Kidney Diseases
- Source Database
- DisGeNET
- Description
- Subsequent multivariable logistic regression analysis with adjustment for covariates as well as a stepwise forward selection procedure revealed that the T --> C (Val591Ala) polymorphism of APOB (rs679899), the -681C --> G polymorphism of PPARG (rs10865710), the T --> C (Cys1367Arg) polymorphism of WRN (rs1346044), the -850C --> T polymorphism of TNF (rs1799724), the -219G --> T polymorphism of APOE (rs405509), the C --> T polymorphism of PTGS1 (rs883484) and the 41A --> G (Glu14Gly) polymorphism of ACAT2 (rs9658625) were significantly (P<0.05) associated with the prevalence of CKD.
- Pubmed
- 19282863
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2009
Drugs