Annotation Detail
Information
- Associated Genes
- TCF7L2
- Associated Variants
-
TCF7L2 c.450+29705T>C
(
ENST00000629706.2,
ENST00000355717.9,
ENST00000545257.6,
ENST00000277945.12,
ENST00000369395.6,
ENST00000627217.3,
ENST00000704414.1,
ENST00000352065.10,
ENST00000369397.8,
ENST00000538897.5,
ENST00000534894.5,
ENST00000355995.9 )
MTNR1B c.223+5596C>G ( ENST00000257068.3 )
GCKR c.1423-418T>C ( ENST00000264717.7 )
TCF7L2 c.450+29705T>C ( ENST00000277945.12, ENST00000352065.10, ENST00000355717.9, ENST00000355995.9, ENST00000369395.6, ENST00000369397.8, ENST00000534894.5, ENST00000538897.5, ENST00000545257.6, ENST00000627217.3, ENST00000629706.2, ENST00000704414.1 )
MTNR1B c.223+5596C>G ( ENST00000257068.3 )
GCKR c.1423-418T>C ( ENST00000264717.7 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- Among Caucasian women, GDM was associated with carriage of TCF7L2 rs7901695, MTNR1B rs10830963 and GCKR rs780094 alleles that are associated with T2DM and fasting glucose in nonpregnant populations.
- Pubmed
- 23456907
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.613988408391434
- Year of publication
- 2014
Drugs