Annotation Detail
Information
- Associated Genes
- HHEX
- Associated Variants
-
rs1111875
KCNQ1 c.1795-11803A>C ( ENST00000713725.1, ENST00000646564.2, ENST00000335475.6, ENST00000155840.12, ENST00000526095.2, ENST00000496887.7 )
MTNR1B c.223+5596C>G ( ENST00000257068.3 )
rs1111875
KCNQ1 c.1795-11803A>C ( ENST00000155840.12, ENST00000335475.6, ENST00000496887.7, ENST00000526095.2, ENST00000646564.2, ENST00000713725.1 )
MTNR1B c.223+5596C>G ( ENST00000257068.3 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- Variants in the KCNQ1 (rs2237895, p = 0.0012), HHEX (rs1111875, p = 0.0024 in Finns) and MTNR1B (rs10830963, p = 0.0039) loci showed the strongest association in patients with low GADA, supporting the hypothesis that the disease in these patients is more like type 2 diabetes.
- Pubmed
- 24906951
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.213843535476095
- Year of publication
- 2014
Drugs