Annotation Detail

Information
Associated Genes
INS
Associated Variants
MTNR1B c.223+5596C>G ( ENST00000257068.3 )
MTNR1B c.223+5596C>G ( ENST00000257068.3 )
Associated Disease
gestational diabetes
Source Database
DisGeNET
Description
rs10830963 was associated cross-sectionally with fasting glucose (p = 0.0069), acute insulin response (AIR; p = 0.0013), disposition index (p = 0.00078), glucose effectiveness (p = 0.018) and gestational diabetes mellitus (OR 1.48; p = 0.012), but not with OGTT 30 min Δinsulin (the difference between the 30 min and fasting plasma insulin concentration) or 30 min insulin-based disposition index.
Pubmed
24728128
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0238208713946101
Year of publication
2014
Drugs