Annotation Detail
Information
- Associated Genes
- SMAD7
- Associated Variants
-
rs10795668
rs4779584
SMAD7 c.743-5183A>G ( ENST00000262158.8, ENST00000589634.1, ENST00000591805.5 )
rs10795668
rs4779584
SMAD7 c.743-5183A>G ( ENST00000262158.8, ENST00000589634.1, ENST00000591805.5 ) - Associated Disease
- colorectal cancer
- Source Database
- DisGeNET
- Description
- Among the European CRC-susceptibility SNPs, rs4939827 in SMAD7 was associated with a significant decreased risk of Korean CRC (age-/gender-adjusted odds ratio [95% confidence interval]: additive model, 0.67 [95% CI, 0.47-0.95]; dominant model, 0.59 [95% CI, 0.39-0.91]). rs4779584 and rs10795668 were associated with CRC risk in females and males, respectively.
- Pubmed
- 23875689
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.162367471351159
- Year of publication
- 2013
Drugs