Annotation Detail

Information
Associated Genes
KLK3
Associated Variants
rs10788160
rs11067228
KLK3 p.Ile179Thr (p.I179T) ( ENST00000326003.7, ENST00000360617.7, ENST00000593997.5, ENST00000595952.5, ENST00000597483.5 )
TERT p.Ala305= (p.A305=) ( ENST00000310581.10, ENST00000334602.10 )
rs10788160
rs11067228
KLK3 p.Ile179Thr (p.I179T) ( ENST00000326003.7, ENST00000360617.7, ENST00000593997.5, ENST00000595952.5, ENST00000597483.5 )
TERT p.Ala305= (p.A305=) ( ENST00000310581.10, ENST00000334602.10 )
Associated Disease
prostate carcinoma
Source Database
DisGeNET
Description
The genotypes of 4 single nucleotide polymorphisms previously associated with serum prostate specific antigen levels (rs2736098, rs10788160, rs11067228 and rs17632542) were determined in 964 healthy Caucasian volunteers without prostate cancer.
Pubmed
23246478
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.08
Year of publication
2013
Drugs