Annotation Detail

Information
Associated Genes
TLR4
Associated Variants
TLR4 MUTATION
TLR4 MUTATION
rs10759931
ENSG00000285082 c.-147-423A>G, TLR4 c.94-787A>G ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 )
rs10759931
ENSG00000285082 c.-147-423A>G, TLR4 c.94-787A>G ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 )
Associated Disease
asthma
Source Database
DisGeNET
Description
The TLR4 single-nucleotide polymorphisms rs1927911, rs10759931, and rs6478317 modified the association of particulate matter and nitrogen dioxide with asthma.
Pubmed
24243740
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0579989362782315
Year of publication
2014
Drugs