Annotation Detail

Information
Associated Genes
RGS4
Associated Variants
RGS4 c.*2001G>A ( ENST00000421743.6, ENST00000367908.8, ENST00000367909.11 )
RGS4 c.*2001G>T ( ENST00000367909.11, ENST00000367908.8, ENST00000421743.6 )
GABRA6 c.*135C>T ( ENST00000274545.10, ENST00000523217.5 )
RGS4 c.*2001G>A ( ENST00000367908.8, ENST00000367909.11, ENST00000421743.6 )
RGS4 c.*2001G>T ( ENST00000367908.8, ENST00000367909.11, ENST00000421743.6 )
GABRA6 c.*135C>T ( ENST00000274545.10, ENST00000523217.5 )
Associated Disease
schizophrenia
Source Database
DisGeNET
Description
Our results suggest that rs3219151 of GABRA6 was associated significantly to decrease the risk of schizophrenia, rs10759 (RGS4) was possible to increase the risk of schizophrenia by miRNA altering the binding of miRNAs to their targets influencing susceptibility to schizophrenia.
Pubmed
23332465
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.216710348810384
Year of publication
2012
Drugs