Annotation Detail
Information
- Associated Genes
- STAT4
- Associated Variants
-
STAT4 c.274-28828C>G
(
ENST00000392320.7,
ENST00000413064.6,
ENST00000358470.8,
ENST00000432798.2,
ENST00000450994.2,
ENST00000714287.1 )
STAT4 c.274-28828C>G ( ENST00000358470.8, ENST00000392320.7, ENST00000413064.6, ENST00000432798.2, ENST00000450994.2, ENST00000714287.1 ) - Associated Disease
- Lupus Erythematosus, Systemic
- Source Database
- DisGeNET
- Description
- To investigate whether the risk allele for systemic lupus erythematosus (SLE) in the signal transducer and activator of transcription factor 4 (STAT4) gene, defined by the single nucleotide polymorphism (SNP) rs10181656(G), is associated with vascular events and/or presence of prothrombotic anti-phospholipid antibodies (aPL) in patients with SLE.
- Pubmed
- 19762360
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.324188177783095
- Year of publication
- 2010
Drugs