Annotation Detail

Information
Associated Genes
CDKN2B-AS1
Associated Variants
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
CDKN2B c.*2619C>T ( ENST00000276925.7 )
rs2157719
rs1412829
rs4977756
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
CDKN2B c.*2619C>T ( ENST00000276925.7 )
rs2157719
rs1412829
rs4977756
Associated Disease
childhood brain tumor
Source Database
DisGeNET
Description
The results indicated that four SNPs, CDKN2BAS rs4977756 (p = 0.036), rs1412829 (p = 0.037), rs2157719 (p = 0.018) and rs1063192 (p = 0.021), were associated with an increased susceptibility to PBTs, whereas the TERT rs2736100 was associated with a decreased risk (p = 0.018).
Pubmed
26014354
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2015
Drugs