Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNFRSF1B p.Met196Arg (p.M196R) ( ENST00000376259.7 )
TNFRSF1B p.Met196Arg (p.M196R) ( ENST00000376259.7 )
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
A polymorphism in high-affinity receptor of TNF (TNFR2) gene, Met196Arg, was reported to be associated with systemic lupus erythematosus (SLE) in Japanese, whereas the association could not be found in Europeans at all and this represents an apparent discrepancy.
Pubmed
11169260
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.120949839602365
Year of publication
2001
Drugs