Annotation Detail
Information
- Associated Genes
- HLA-DPB1
- Associated Variants
-
HLA-DPB1 c.*550A>G
(
ENST00000416804.2,
ENST00000428835.6,
ENST00000418931.7 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000418931.7, ENST00000428835.6 ) - Associated Disease
- Hepatitis B, Chronic
- Source Database
- DisGeNET
- Description
- The genome-wide association study (GWAS) variant (rs9277535; 550A/G) in the 3'UTR of the HLA-DPB1 gene that associated most significantly with chronic hepatitis B and outcomes to HBV infection in Asians had a marginal effect on HBV recovery in our European- and African-American samples (odds ratio [OR] = 0.39, P = 0.01, combined ethnic groups).
- Pubmed
- 22496224
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.25090128214493
- Year of publication
- 2012
Drugs