Annotation Detail

Information
Associated Genes
GCA
Associated Variants
FLT1 c.3815+976C>T ( ENST00000282397.9 )
rs833061
FLT1 c.3815+976C>T ( ENST00000282397.9 )
rs833061
Associated Disease
colorectal carcinoma
Source Database
DisGeNET
Description
The VEGFA rs833061 SNP is associated with the ORR, and the FLT1 rs9513070 SNP and FLT1 GCA haplotypes are associated with PFS and OS in advanced CRC patients treated with cytotoxic chemotherapy plus bevacizumab.
Pubmed
25139485
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2014
Drugs