Annotation Detail

Information
Associated Genes
TSBP1
Associated Variants
TSBP1 p.Lys400Gln (p.K400Q) ( ENST00000375015.8, ENST00000442822.6, ENST00000447241.6, ENST00000527965.5, ENST00000533191.6 )
TSBP1 p.Lys400Gln (p.K400Q) ( ENST00000375015.8, ENST00000442822.6, ENST00000447241.6, ENST00000527965.5, ENST00000533191.6 )
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
[We identified and then confirmed through replication two new genetic loci for SLE: a promoter-region allele associated with reduced expression of BLK and increased expression of C8orf13 and variants in the ITGAM-ITGAX region.]
Pubmed
18204098
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.00946812791440812
Year of publication
2008
Drugs