Annotation Detail
Information
- Associated Genes
- DICER1
- Associated Variants
-
DICER1 c.*2693A>G
(
ENST00000526495.6,
ENST00000531162.7,
ENST00000674628.2,
ENST00000343455.8,
ENST00000529720.2 )
DICER1 c.*2693A>G ( ENST00000343455.8, ENST00000526495.6, ENST00000529720.2, ENST00000531162.7, ENST00000674628.2 ) - Associated Disease
- colorectal carcinoma
- Source Database
- DisGeNET
- Description
- Finally, we observed that homozygous CC genotype of DICER1, rs1057035, was significantly associated with decreased risk of CRC (odds ratio = 0.49; 95% confidence interval: 0.25-0.95, P = 0.036) when compared to TT homozygote genotype; also, the C allele tended to have a protective effect (P = 0.072).
- Pubmed
- 23441612
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
- Year of publication
- 2013
Drugs