Annotation Detail

Information
Associated Genes
STAT4
Associated Variants
STAT4 c.274-23582A>C ( ENST00000392320.7, ENST00000358470.8, ENST00000413064.6, ENST00000432798.2, ENST00000450994.2, ENST00000714287.1 )
STAT4 c.274-23582A>C ( ENST00000358470.8, ENST00000392320.7, ENST00000413064.6, ENST00000432798.2, ENST00000450994.2, ENST00000714287.1 )
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
A recent study in the North American White population has documented the association of a common STAT4 haplotype (tagged by rs7574865) with risk for rheumatoid arthritis (RA) and systemic lupus erythematosus.
Pubmed
17932559
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.324188177783095
Year of publication
2007
Drugs