Annotation Detail

Information
Associated Genes
FCRL3
Associated Variants
rs7528684
rs7528684
Associated Disease
Graves Disease
Source Database
DisGeNET
Description
Above data indicated that FCRL3 gene and its proxy SNP rs7528684 may be involved in the pathogenesis of GD by excessive inhibiting B cell receptor signaling and the impairment of suppressing function of Tregs.
Pubmed
23505439
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.248729747168288
Year of publication
2013
Drugs