Annotation Detail
Information
- Associated Genes
- CDH1
- Associated Variants
-
CDH1 MUTATION
CDH1 MUTATION - Associated Disease
- Secondary malignant neoplasm of ovary
- Source Database
- DisGeNET
- Description
- Both the primary tumor and ovarian metastasis have common biallelic loss-of-function of both the CDH1 and TP53 tumor suppressors, indicating a common genetic origin.
- Pubmed
- 25315765
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs