Annotation Detail

Information
Associated Genes
IL17RC
Associated Variants
ENSG00000288550 p.Ser111Leu (p.S111L), IL17RC p.Ser182Leu (p.S182L) ( ENST00000295981.7, ENST00000383812.9, ENST00000403601.8, ENST00000413608.2, ENST00000416074.6, ENST00000438091.6, ENST00000451165.7, ENST00000455057.5, ENST00000483582.5, ENST00000696816.1, ENST00000696823.1, ENST00000696824.1, ENST00000696825.1, ENST00000696826.1, ENST00000696828.1, ENST00000696830.1, ENST00000696832.1 )
ENSG00000288550 p.Ser111Leu (p.S111L), IL17RC p.Ser182Leu (p.S182L) ( ENST00000295981.7, ENST00000383812.9, ENST00000403601.8, ENST00000413608.2, ENST00000416074.6, ENST00000438091.6, ENST00000451165.7, ENST00000455057.5, ENST00000483582.5, ENST00000696816.1, ENST00000696823.1, ENST00000696824.1, ENST00000696825.1, ENST00000696826.1, ENST00000696828.1, ENST00000696830.1, ENST00000696832.1 )
Associated Disease
Parasitemia
Source Database
DisGeNET
Description
Genotype-phenotype correlations between SNPs and clinical parameters revealed that genotypes of rs708567 (IL17RC) correlate with parasitemia (P=0.028, r(2)=0.0086), with GG homozygotes having the lowest parasite burden.
Pubmed
22673309
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2012
Drugs