Annotation Detail
Information
- Associated Genes
- STAT5B
- Associated Variants
-
STAT5B MUTATION
STAT5B MUTATION - Associated Disease
- Lipomatosis, Multiple
- Source Database
- DisGeNET
- Description
- We previously identified a target gene, LPP/miR-28 (LIM domain containing preferred translocation partner in lipoma), induced by constitutive activation of STAT5, but not by transient cytokine-activated STAT5. miR-28 exerts negative effects on thrombopoietin receptor signaling and platelet formation.
- Pubmed
- 24681953
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs