Annotation Detail
Information
- Associated Genes
- MYC
- Associated Variants
-
rs6983267
(
ENST00000645438.1 )
rs6983267 ( ENST00000645438.1 ) - Associated Disease
- colorectal cancer
- Source Database
- DisGeNET
- Description
- The single nucleotide polymorphism (SNP) rs6983267 on chromosome 8q24 is a CRC susceptibility locus that affects binding activity of transcription factor 7 like-2 (TCF7L2) to CTNNB1, thereby altering expression of target oncogenes, including MYC.
- Pubmed
- 24317174
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.011324613757252
- Year of publication
- 2014
Drugs