Annotation Detail
Information
- Associated Genes
- F2R
- Associated Variants
-
F2R MUTATION
F2R MUTATION - Associated Disease
- Ischemic Cerebrovascular Accident
- Source Database
- DisGeNET
- Description
- Collectively, this study reveals the importance of APC glycosylation in controlling the efficacy of PAR1 proteolysis by APC and demonstrates the potential of novel APC variants with superior cytoprotective signaling function as enhanced therapeutic agents for the treatment of ischemic stroke.
- Pubmed
- 26084674
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs