Annotation Detail

Information
Associated Genes
F2R
Associated Variants
F2R MUTATION
F2R MUTATION
Associated Disease
Ischemic Cerebrovascular Accident
Source Database
DisGeNET
Description
The cytoprotective effects are protease activated receptor 1 (PAR-1) and endothelial protein C receptor (EPCR) dependent and likely underlie protective effects of APC in animal models of sepsis, myocardial infarction and ischemic stroke.
Pubmed
25032959
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs