Annotation Detail
Information
- Associated Genes
- PECAM1
- Associated Variants
- PECAM1 MUTATION
- Associated Disease
- malaria
- Source Database
- DisGeNET
- Description
- Interestingly, a SNP of the PECAM1 gene (rs668, exon 3, C/G) with low minor allele frequency in populations of the endemic region compared to the non-endemic region exhibited differential association with disease in these regions; the G allele was a risk factor for malaria in the endemic region, but exhibited significant association with protection from disease in the non-endemic region.
- Pubmed
- 19055786
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00318135759484294
- Year of publication
- 2008
Drugs