Annotation Detail
Information
- Associated Genes
- PON1
- Associated Variants
-
PON1 MUTATION
PON1 MUTATION
PON1 p.Gln192Arg (p.Q192R) ( ENST00000222381.8 )
PON1 p.Gln192Arg (p.Q192R) ( ENST00000222381.8 ) - Associated Disease
- Dementia, Vascular
- Source Database
- DisGeNET
- Description
- Synergistic epistasis of paraoxonase 1 (rs662 and rs85460) and apolipoprotein E4 genes in pathogenesis of Alzheimer's disease and vascular dementia.
- Pubmed
- 24965284
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00563426596522981
- Year of publication
- 2015
Drugs