Annotation Detail
Information
- Associated Genes
- APOE
- Associated Variants
-
APOE MUTATION
APOE MUTATION
PON1 p.Gln192Arg (p.Q192R) ( ENST00000222381.8 )
PON1 p.Gln192Arg (p.Q192R) ( ENST00000222381.8 ) - Associated Disease
- Dementia, Vascular
- Source Database
- DisGeNET
- Description
- The interaction between PON1 genes (rs662 and rs85460) and ApoE genes showed synergistic epistasis in altering the odds of significantly having both AD and VaD.
- Pubmed
- 24965284
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.070704503614275
- Year of publication
- 2015
Drugs