Annotation Detail

Information
Associated Genes
STAT1
Associated Variants
rs6590330
rs6590330
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
We propose a model in which the risk allele of rs6590330 is associated with decreased ETS1 expression and increases SLE risk by enhancing the binding of pSTAT1.
Pubmed
25865496
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0074484826780071
Year of publication
2015
Drugs