Annotation Detail
Information
- Associated Genes
- IL1A
- Associated Variants
-
IL1A MUTATION
IL1A MUTATION - Associated Disease
- Cryopyrin-Associated Periodic Syndromes
- Source Database
- DisGeNET
- Description
- The use of IL-1-antagonists has been associated with beneficial effects in a large number of HAID associated with excessive IL-1 signalling, such as cryopyrin-associated periodic syndromes, familial Mediterranean fever, and deficiency of IL-1 receptor antagonist.
- Pubmed
- 25149390
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00515739556952576
Drugs