Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
TNF MUTATION
TNF MUTATION - Associated Disease
- liver carcinoma
- Source Database
- DisGeNET
- Description
- Taken together, these findings demonstrate that TIPE2 was able to suppress TNF-α-induced hepatocellular carcinoma metastasis by inhibiting Erk1/2 and NF-κB activation, indicating that both TNF-α and TIPE2 might be potential targets for the treatment of HCC metastasis.
- Pubmed
- 25339267
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0580014793216416
Drugs