Annotation Detail
Information
- Associated Genes
- TNFSF10
- Associated Variants
-
TNFSF10 MUTATION
TNFSF10 MUTATION - Associated Disease
- liver carcinoma
- Source Database
- DisGeNET
- Description
- Expression of Bcl-xL, cIAP2, survivin and Raf-1 was downregulated following silencing of SNAIL, while down-regulation of any of the proteins contributed to SNAIL suppression enhancing HCC cell sensitivity to TRAIL‑induced apoptosis, with the exception of cIAP2.
- Pubmed
- 25607597
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 13
- Original source reporting the Gene Disease association
- BeFree,CTD_human,LHGDN
- DisGENET score for the Gene Disease association
- 0.149646753186738
Drugs