Annotation Detail

Information
Associated Genes
MMP9
Associated Variants
MMP9 MUTATION
MMP9 MUTATION
Associated Disease
liver carcinoma
Source Database
DisGeNET
Description
In this study, we report that MUC1 overexpression enhanced the levels of phosphorylated Smad3 linker region (p-Smad3L) (Ser-213) and its target gene MMP-9 in HCC cells, suggesting that MUC1 mediates TGF-β signaling.
Pubmed
25526895
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.159005260490971
Drugs