Annotation Detail

Information
Associated Genes
MMP9
Associated Variants
MMP9 MUTATION
MMP9 MUTATION
Associated Disease
liver carcinoma
Source Database
DisGeNET
Description
Metformin was also found to significantly inhibit the expression and secretion of MMP-9 and uPA in HCC cells, and suppress the phosphorylation of ERK1/2 and JNK1/2.
Pubmed
25245054
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.159005260490971
Drugs