Annotation Detail

Information
Associated Genes
ABCB1
Associated Variants
ABCB1 MUTATION
ABCB1 MUTATION
Associated Disease
liver carcinoma
Source Database
DisGeNET
Description
Taken together, we clarify that ZHX2 represses NF-Y-mediated activation of MDR1 transcription and, in doing so, enhances the effects of chemotherapeutics in HCC cells both in vitro and in vivo.
Pubmed
25473899
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.143102353691818
Drugs