Annotation Detail

Information
Associated Genes
HNF1B
Associated Variants
HNF1B c.345-1526G>A ( ENST00000617811.5, ENST00000614313.4, ENST00000621123.4, ENST00000613727.4 )
WFS1 c.713-1075C>G ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
HNF1B c.345-1526G>A ( ENST00000613727.4, ENST00000614313.4, ENST00000617811.5, ENST00000621123.4 )
WFS1 c.713-1075C>G ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
Not only did an association between WFS1-rs6446482 and early-onset T2D exist in the subgroup analysis, but TCF2-rs7501939 and WFS1-rs6446482 were also confirmed to confer risk for T2D in this meta-analysis.
Pubmed
20509872
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.564132095956303
Year of publication
2010
Drugs