Annotation Detail

Information
Associated Genes
JUN
Associated Variants
JUN MUTATION
JUN MUTATION
Associated Disease
liver carcinoma
Source Database
DisGeNET
Description
We showed that CREBH activated by HBx interacted with HBx protein, leading to a synergistic effect on the expression of AP-1 target genes and the proliferation of HCC cells and mouse primary hepatocytes.
Pubmed
25428452
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.128434561077818
Drugs