Annotation Detail

Information
Associated Genes
MAPT
Associated Variants
MAPT p.Asn688His (p.N688H) ( ENST00000574436.5, ENST00000571987.5, ENST00000351559.10, ENST00000262410.10, ENST00000535772.6, ENST00000431008.7, ENST00000344290.10, ENST00000415613.6, ENST00000420682.7, ENST00000446361.7, ENST00000334239.12, ENST00000680674.1 )
MAPT p.Asn688His (p.N688H) ( ENST00000344290.10, ENST00000351559.10, ENST00000446361.7, ENST00000262410.10, ENST00000334239.12, ENST00000415613.6, ENST00000420682.7, ENST00000431008.7, ENST00000535772.6, ENST00000571987.5, ENST00000574436.5, ENST00000680674.1 )
Associated Disease
Parkinsonian Disorders
Source Database
DisGeNET
Description
Familial frontotemporal dementia and parkinsonism with a novel N296H mutation in exon 10 of the tau gene and a widespread tau accumulation in the glial cells.
Pubmed
11585254
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.169687301415552
Year of publication
2001
Drugs