Annotation Detail

Information
Associated Genes
CDKN2A
Associated Variants
CDKN2A MUTATION
CDKN2A MUTATION
Associated Disease
Precursor Cell Lymphoblastic Leukemia Lymphoma
Source Database
DisGeNET
Description
Deletions of EBF1, IKZF1, and CDKN2A/B have an independent adverse prognosis for adolescents and adults with B-precursor ALL, and this suggests that these CNAs should be included in the initial risk assessment of ALL.
Pubmed
26194343
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,GWASCAT,LHGDN
DisGENET score for the Gene Disease association
0.274751948104533
Drugs