Annotation Detail
Information
- Associated Genes
- KMT2A
- Associated Variants
-
KMT2A MUTATION
KMT2A MUTATION - Associated Disease
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
- Source Database
- DisGeNET
- Description
- They act as dominant cooperating oncoproteins that cause acute leukemias bearing MLL translocations and to a lesser extent T-cell acute lymphocytic leukemia (ALL) characterized by other gene fusions.
- Pubmed
- 26059450
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00380018620912425
Drugs