Annotation Detail
Information
- Associated Genes
- HTR2A
- Associated Variants
-
HTR2A p.His452Tyr (p.H452Y)
(
ENST00000543956.5,
ENST00000542664.4 )
HTR2A p.His452Tyr (p.H452Y) ( ENST00000542664.4, ENST00000543956.5 ) - Associated Disease
- schizophrenia
- Source Database
- DisGeNET
- Description
- Our results suggest that HTR2A rs6314 affects 5-HT2AR expression and functionally contributes to genetic modulation of known endophenotypes of schizophrenia-like higher-level cognitive behaviors and related prefrontal activity, as well as response to treatment with olanzapine.
- Pubmed
- 23842608
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.341213462521366
- Year of publication
- 2013
Drugs