Annotation Detail
Information
- Associated Genes
- MAOA
- Associated Variants
-
HTR2A c.-329+609G>A
HTR2A c.-329+609G>A - Associated Disease
- heroin dependence
- Source Database
- DisGeNET
- Description
- By MDR (Multifactor Dimensionality Reduction) analyses, the interactive effects between MAOA-LPR and 5-HTTVNTR, and among MAOA-LPR, 5-HTTVNTR and rs6311 were close to the significance level (P=0.05) in predicting the risk of co-morbidity of BPD and heroin dependence relative to normal female controls, with 1000-fold permutation testing P-value<0.06 however >0.05 respectively.
- Pubmed
- 24355137
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00554838957344497
- Year of publication
- 2013
Drugs