Annotation Detail

Information
Associated Genes
HTR2A
Associated Variants
HTR2A c.614-2211T>C ( ENST00000543956.5, ENST00000542664.4 )
HTR2A c.-329+609G>A
HTR2A c.614-2211T>C ( ENST00000542664.4, ENST00000543956.5 )
HTR2A c.-329+609G>A
Associated Disease
Unipolar Depression
Source Database
DisGeNET
Description
The 5HT2A receptor gene (HTR2A) polymorphisms rs7997012 and rs6311 have in some earlier studies been associated with serotonin selective reuptake inhibitor (SSRI) treatment response in major depressive disorder (MDD), but the findings are inconsistent.
Pubmed
21741447
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.011324613757252
Year of publication
2011
Drugs