Annotation Detail
Information
- Associated Genes
- HTR1A
- Associated Variants
-
HTR1A c.-1019G>C
HTR1A c.-1019G>C - Associated Disease
- depressive disorder
- Source Database
- DisGeNET
- Description
- In humans, the G variant of the C(-1019)G 5-HT1A receptor promoter gene polymorphism (rs6295) has been associated with higher expression of 5-HT1A receptors, increased depression, and lower stress preceding completed suicide.
- Pubmed
- 21397953
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0114005586273727
- Year of publication
- 2011
Drugs