Annotation Detail

Information
Associated Genes
HTR1A
Associated Variants
HTR1A c.-1019G>C
HTR1A c.-1019G>C
Associated Disease
Unipolar Depression
Source Database
DisGeNET
Description
Serotonin 1A (5-HT1A) binding potential (BP) as assessed by positron emission tomography (PET) is higher in major depressive disorder (MDD) in association with the higher expressing GG genotype of the 5-HT1A C-1019G polymorphism.
Pubmed
16395308
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0114005586273727
Year of publication
2006
Drugs