Annotation Detail
Information
- Associated Genes
- KRAS
- Associated Variants
-
KRAS c.*2626T>G
(
ENST00000256078.10,
ENST00000688940.1,
ENST00000553788.6,
ENST00000692768.1,
ENST00000685328.1,
ENST00000693229.1,
ENST00000311936.8 )
KRAS c.*2626T>G ( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1, ENST00000553788.6 ) - Associated Disease
- ovarian carcinoma
- Source Database
- DisGeNET
- Description
- Recently, a variant allele in the 3'UTR of the KRAS gene (rs61764370 T>G) was shown to be associated with an increased risk for developing non-small cell lung cancer, as well as ovarian cancer, and was most enriched in ovarian cancer patients from hereditary breast and ovarian cancer families.
- Pubmed
- 20676756
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00651460492992728
- Year of publication
- 2011
Drugs