Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF MUTATION
TNF MUTATION
Associated Disease
IMMUNE SUPPRESSION
Source Database
DisGeNET
Description
This suggests that the protective effect of Fn14 blockade in allo-HCT is based on the protection of intestinal cells from TNF-induced apoptosis and not due to immune suppression.
Pubmed
26012567
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Drugs