Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET MUTATION
RET MUTATION
Associated Disease
familial medullary thyroid carcinoma
Source Database
DisGeNET
Description
Systematic prophylactic total thyroidectomy in patients with a RET proto-oncogene mutation allowed early diagnosis of MTC in one-third of cases.
Pubmed
24993783
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree,CLINVAR,CTD_human,ORPHANET,UNIPROT
DisGENET score for the Gene Disease association
0.521802048300367
Drugs