Annotation Detail
Information
- Associated Genes
- TLR4
- Associated Variants
-
TLR4 MUTATION
TLR4 MUTATION - Associated Disease
- Peripheral Arterial Diseases
- Source Database
- DisGeNET
- Description
- Our aim is to study a transcriptional activation pathway of the innate immune system through the cellular signalling cascade triggered by receptors Toll-like receptor 2 (TLR2) and Toll-like receptor 4 (TLR4) of endothelial cells after the exposure of these cells to seropositive ABGPI human serum obtained from PAD patients.
- Pubmed
- 24472415
- Section of the abstract supporting the evidence
- OBJECTIVE
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs