Annotation Detail

Information
Associated Genes
APOA1
Associated Variants
APOA1 MUTATION
APOA1 MUTATION
Associated Disease
Hypoalphalipoproteinemia, Familial
Source Database
DisGeNET
Description
Dalcetrapib increased high-density lipoprotein cholesterol (HDL-C) and ApoA1 levels to a similar extent in FHA (+22.8, +13.9%) and FCH (+18.4, +12.1%), both p < 0.001 vs. placebo.
Pubmed
25281277
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree,CLINVAR,ORPHANET
DisGENET score for the Gene Disease association
0.242171534976642
Drugs