Annotation Detail

Information
Associated Genes
TLR4
Associated Variants
TLR4 MUTATION
TLR4 MUTATION
Associated Disease
Macular dystrophy, corneal type 1
Source Database
DisGeNET
Description
Both in microalbuminuria and in overt DN, TLR4 mRNA and protein were overexpressed 4- to 10-fold in glomeruli and tubules compared with the control kidney and in MCD.
Pubmed
24786705
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs