Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
-
MGMT MUTATION
MGMT MUTATION - Associated Disease
- Glioblastoma multiforme
- Source Database
- DisGeNET
- Description
- Currently, O6-methylguanine-DNA methyltransferase(MGMT) promoter methylation is the most convincing predictive biomarker for temozolomide (TMZ) response in patients with glioblastoma multiforme (GBM).
- Pubmed
- 25890369
- Section of the abstract supporting the evidence
- BACKGROUND
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0105862330111318
Drugs